Advances in tissue-engineered skin substitutes

2011, Vol 2, No 1, pages 27–34

Large skin defects resulting from burns, trauma, congenital giant nevi, and disease can lead to skin necrosis and represent a challenge to achieving skin coverage. This article summarises the development of tissue-engineered skin substitutes, identifies key clinical landmarks, reviews some critical aspects of cell and skin biology and highlights future developments that may foster progress in engineered skin.

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