The role of proteases in wound diagnostics
Assessment and diagnosis | Expert working group review
This consensus document explores the role of proteases in wound healing and the value of having an easy to use, point-of-care protease test in clinical practice.
An international group of experts met in Cape Town, South Africa in February 2011 at the Wounds International Conference to build on the 2008 World Union of Wound Healing Societies (WUWHS) consensus document Diagnostics and wounds. The goal was to explore the importance of protease activity in wound healing and to gain consensus on the value of having an easy to use, point-of-care protease test in clinical practice.
The key to success for such a test will be for clinicians to know clearly when, how and why to use such a test. The expert consensus opinion of the meeting participants reaffirmed increased protease activity as currently the best available marker for impaired wound healing when other causes have been excluded, and that effective use of a protease test kit at the point of care has the potential to change wound care globally.
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This document was supported by an unrestricted educational grant from Systagenix.